Ddb1- and cul4-associated factor 5

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August undefined, 2024

WebApr 14, 2024 · Cullin-RING E3 ubiquitin ligase (CRL)-4 is a member of the large CRL family in eukaryotes. It plays important roles in a wide range of cellular processes, organismal development, and physiological and pathological conditions. DDB1- and CUL4-associated factor 8 (DCAF8) is a WD40 repeat-containing protein, which serves as a substrate … WebDDB1- and CUL4-associated factor 8-like protein 2 isoform X1: starting from $99.00: NM_008821.2: NP_032847.2: DDB1- and CUL4-associated factor 8-like protein 2: starting from $99.00: Learn more about the CRISPR gRNA constucts. Legal Statement of GenCRISPR Services and Products (Updated on July 28, 2015):

DCAF5 DDB1 and CUL4 associated factor 5 [ (human)]

Web5.1.2 DDB1. DDB1 is a binding ... More than 20 partner proteins of DDB1, collectively called DDB1- and CUL4-associated factors ... Binding of CSB recruits E3 ubiquitin ligase CRL4CSA, consisting of DDB1, CUL4, RBX1, and CSA (red). Stalled RNAP is then able to backtrack with the help of remodeling and sliding of upstream nucleosomes, facilitated ... WebApr 12, 2024 · The damaged DNA-binding protein 1 (DDB1) enhances the survival and maintenance of multipotent cells through promoting the Cullin 4 E3 ligase complex-dependent ubiquitination and subsequent degradation of downstream substrates. Naive T cells could be activated and differentiated into effector and memory T cells by exogenous … hetax käse wikipedia

DCAF5 Gene - GeneCards DCAF5 Protein DCAF5 …

WebMay 24, 2004 · DDB1- and CUL4-associated factor 5 Gene Dcaf5 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 946 Protein existence Evidence at protein level Annotation score 3/5 Entry Feature viewer Publications External links History BLAST Download Add Add a publication Entry feedback Function WebDec 8, 2024 · DDB1- and CUL4-associated factor 5, WD repeat domain 22, WD repeat-containing protein 22 GeneRIFs: Gene References Into Functions Knockdown of L3MBTL3 or DCAF5 is sufficient to restore the protein levels of SOX2 and rescue the defects of mouse embryonic stem cells caused by LSD1 or PHF20L1 deficiency. heteka tuoli

DDB1- and CUL4-associated factor 5 - Medical Dictionary

WebMouse Gene Ddb1 (ENSMUST00000025649.9) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default) Description: Mus musculus damage specific DNA binding protein 1 (Ddb1), mRNA. (from RefSeq NM_015735) ... Full=UV-damaged DNA-binding factor; WebFeb 15, 2005 · DDB1- and CUL4-associated factor 17. Gene. DCAF17. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 520. Protein existence. Evidence at protein level. Annotation score. 5/5. Entry. Feature viewer. Publications. External links. History. BLAST Align. Download. Add Add a publication … hetaxkäseWebSep 30, 2024 · The cullin-4-based RING-type (CRL4) family of E3 ubiquitin ligases functions together with dedicated substrate receptors. Out of the ˜29 CRL4 substrate receptors reported, the DDB1- and CUL4-associated factor 1 (DCAF1) is essential for cellular survival and growth, and its deregulation has been implicated in tumorigenesis. We … het balkon maassluis

"WebNov 27, 2015 · Some of the previous identified substrates have been associated with cell cycle control and DNA damage, however Kronke et al. demonstrates that two lymphoid transcription factors (IKZF1 and IKZF3) … " - Ddb1- and cul4-associated factor 5

Ddb1- and cul4-associated factor 5

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WebDDB1 and CUL4 associated factor 17. Normal Function. The DCAF17 gene provides instructions for making a protein whose function is unknown. The gene is active (expressed) in several organs and tissues in the body, including the brain, skin, and liver. Within cells, the protein produced from this gene is found in the nucleolus, which is a small ... WebApr 5, 2024 · DTL是CUL4-DDB1相关因子（DDB1 and CUL4 associated factor，DCAF）之一，可能参与恶性肿瘤的发展过程[2]。Cullin-RING E3泛素连接酶（Cullin-RING E3 ligase，CRL）拥有庞大的家族，参与基因转录、细胞周期调控、细胞分化、增殖、凋亡和肿瘤发生等过程[3]。DTL作为连接酶中的底物 ...

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WebAug 31, 2024 · The WD40-repeat containing proteins, including DDB1–CUL4-associated factors (DCAFs), are abundant and conserved proteins that play important roles in different cellular processes including spermatogenesis. DCAFs are subset of WD40 family proteins that contain WDxR motif and have been proposed to function as substrate receptor for … WebMar 21, 2024 · GeneCards Summary for DCAF7 Gene. DCAF7 (DDB1 And CUL4 Associated Factor 7) is a Protein Coding gene. Diseases associated with DCAF7 include Noonan Syndrome 4 and Abdominal Obesity-Metabolic Syndrome 3 . Among its related pathways are Chaperonin-mediated protein folding and Metabolism of proteins .

WebDDB1- and CUL4-associated factor 5, WD repeat-containing protein 22, breakpoint cluster region protein, uterine leiomyoma, 2 GeneRIFs: Gene References Into Functions Observational study of gene-disease association. (HuGE Navigator) Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) WebMar 21, 2024 · DCAF4L2 (DDB1 And CUL4 Associated Factor 4 Like 2) is a Protein Coding gene. Diseases associated with DCAF4L2 include Robinow Syndrome, Autosomal Recessive 1. An important paralog of this gene is DCAF4. Additional gene information for DCAF4L2 Gene. HGNC (26657) NCBI Entrez Gene (138009)

WebThe cullin 4 (CUL4)-damage-specific DNA binding protein 1 (DDB1)-cereblon (CRBN) E3 ubiquitin ligase co-exists in the same complex with and promotes the degradation of ClC-2 channels. The CRBN-targeting immunomodulatory drug lenalidomide and the cullin E3 ligase inhibitor MLN4924 promotes and attenuates, respectively, proteasomal … WebPharos : Target Details - DCAF5 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data

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WebMar 29, 2024 · DCAF5DDB1 and CUL4 associated factor 5 [ Homo sapiens(human) ] Gene ID: 8816, updated on 23-Sep-2024 Download Datasets Gene Sequences (FASTA) Transcript sequences (FASTA) Protein sequences(FASTA) In addition, your package will include a detailed data report in both TSV and JSONL formats. heta vitlöksräkorWebDCAF5 DDB1 and CUL4 associated factor 5 [ (human)] Gene ID: 8816, updated on 8-Dec-2024 Summary Predicted to be involved in protein ubiquitination. Part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr … hete kip uit oma\u0027s keukenWebThe gene, DGKH, encodes a member of the diacylglycerol kinase enzyme family , while DCAF5 encodes DDB1 and CUL4-associated factor 5 , and LINC02261 is a non-protein-coding lncRNA. None of the genes are known susceptibility loci … heta yrjänäinenWebJan 10, 2024 · DCAF8L2 (DDB1 And CUL4 Associated Factor 8 Like 2) is a Protein Coding gene. An important paralog of this gene is DCAF8L1. Additional gene information for DCAF8L2 Gene HGNC (31811) NCBI Entrez Gene (347442) Ensembl (ENSG00000189186) UniProtKB/Swiss-Prot (P0C7V8) Open Targets Platform (ENSG00000189186) Alliance … heta ytor skyltWebOct 4, 2024 · Among E3 ubiquitin ligases known to be involved in the ubiquitination of Nrf2, DDB1 and Cullin4 associated factor 11 (DCAF11) was down-regulated at both protein and mRNA levels in stable cells, indicating that the repression of DCAF11 by TFEB may be mainly involved in the stabilization of Nrf2. ... DDB1 and CUL4 associated factor 11, … heta ytorWebDCAF12 (CT102, DKFZP434O125, KIAA1892, MGC1058, TCC52, WDR40A) protein expression summary. hetbalkonvan maassluis.nlWebAug 31, 2024 · Background: The WD40-repeat containing proteins, including DDB1-CUL4-associated factors (DCAFs), are abundant and conserved proteins that play important roles in different cellular processes including spermatogenesis. DCAFs are subset of WD40 family proteins that contain WDxR motif and have been proposed to function as … heteka sänky